陈丽建,女,1988年5月生,山东莱芜人,理学博士,永利集团3044am官方入口副研究员。
主要从事先进功能纳米材料的制备、功能化及其在生物成像中的应用,以及食品致病菌等有害物的检测和光动力杀菌的研究。以第一作者或共同通讯作者身份在国际学术期刊上发表SCI论文11篇;主持国家和省部级科研项目4项,参与国家重点自然科学基金项目两项;以第一发明人申请国家发明专利五项,其中授权两项。
工作经历
永利集团3044am官方入口,副研究员,2022.6至今
永利集团3044am官方入口,助理研究员,2020.4-2022.5
永利集团3044am官方入口,博士后,导师:严秀平教授,2017.12-2020.4
青岛大学转化医学研究院,讲师,2017.7-2017.12
教育背景
南开大学(分析化学专业),博士,2014.9-2017.6
山东农业大学(分析化学专业),硕士,2011.9-2014.6
山东农业大学(材料化学专业),本科,2007.9-2011.6
1.主持国家自然科学基金青年项目“生物膜伪装近红外有机长余辉纳米探针用于炎症与动脉粥样硬化易损斑块成像”(21804057)
2.主持江苏省自然科学基金青年项目“仿生近红外有机长余辉纳米探针的制备及其光学成像研究”(BK20180584)
3.主持中国博士后基金一等面上项目“白细胞膜包被长余辉纳米探针用于炎症靶向成像与治疗”(2018M630509)
4.获中国博士后创新人才支持计划资助“多功能近红外长余辉纳米探针用于荧光成像检测食源性致病细菌”(BX20180130)
5.主持永利集团3044am官方入口基本科研计划青年基金“基于光响应纳米材料的高效富集型微针贴片用于生鲜食品新鲜度的快速灵敏检测”(JUSRP121005)
代表性论文
1.Jia-Hua Gong,Li-Jian Chen,*Xu Zhao, and Xiu-Ping Yan*. Persistent Production of Reactive Oxygen Species with Zn2GeO4:Cu Nanorod-Loaded Microneedles for Methicillin-ResistantStaphylococcus AureusInfectious Wound Healing.ACS Applied Materials & Interfaces. 2022, 14, 17142-17152.
2.Li-Jian Chen, Yao-Yao Liu, Xu Zhao, and Xiu-Ping Yan*. Vancomycin-Functionalized Porphyrinic Metal-Organic Framework PCN-224 with Enhanced Antibacterial Activity againstStaphylococcus Aureus.Chemistry-An Asian Journal, 2021,16, 2022-2026.
3.Yao-Yao Liu,Li-Jian Chen,*Xu Zhao, and Xiu-Ping Yan* Effect of Topology on Photodynamic Sterilization of Porphyrinic Metal-Organic Frameworks.Chemistry - A European Journal2021, 27, 10151-10159.
4.Li-Jian Chen, Xu Zhao, Yao-Yao Liu, Xiu-Ping Yan*. Macrophage Membrane Coated Persistent Luminescence Nanoparticle@MOF Derived Mesoporous Carbon Core-Shell Nanocomposites for Autofluorescence-Free Imaging-Guided Chemotherapy.Journal of Materials Chemistry B2020, 8, 8071-8083.
5.Li-Jian Chen, Xu Zhao, Xiu-Ping Yan*. Cell-Penetrating Peptide-Functionalized Persistent Luminescence Nanoparticles for Tracking J774A.1 Macrophages Homing to Inflamed Tissues.ACS Applied Materials & Interfaces. 2019, 11, 19894-19901.
6.Li-Jian Chen, Cheng-Xiong Yang, Xiu-Ping Yan*. Liposome-Coated Persistent Luminescence Nanoparticles as Luminescence Trackable Drug Carrier for Chemotherapy.Analytical Chemistry. 2017, 89, 6936-6939.
7.Li-Jian Chen, Shao-Kai Sun, Yong Wang, Cheng-Xiong Yang, Shu-Qi Wu, Xiu-Ping Yan*. Activatable Multifunctional Persistent Luminescence Nanoparticle/Copper Sulfide Nanoprobe forIn VivoOptical Imaging-Guided Photothermal Therapy.ACS Applied Materials & Interfaces, 2016, 8, 32667-32674.
8.Li-Jian Chen, Kai-Fang Sun, Pei-Pei Li, Xian-Zhong Fan, Jian-Chao Sun and Shi-Yun Ai*. DNA-Enhanced Peroxidase-Like Activity of Layered Double Hydroxides Nanosheets and Applications in H2O2and Glucose Sensing.Nanoscale, 2013, 5, 10982-10988.
9.Li-Jian Chen, Bing Sun,Xin-Dong Wang,Feng-Min Qiaoand Shi-Yun Ai*. 2D Ultrathin Nanosheets of Co-Al Layered Double Hydroxides Prepared inL-Asparagine Solution: Enhanced Peroxidase-Like Activity and Colorimetric Detection of Glucose.Journal of Materials ChemistryB, 2013, 1, 2268-2274.
10.Li-Jian Chen,Na Wu,Bing Sun,Hai-Chao Su,Shi-Yun Ai*. Colorimetric Detection of Peroxynitrite-Induced DNA Damage Using Gold Nanoparticles, and on The Scavenging Effects of Antioxidants.Microchimica Acta, 2013, 180: 573-580.
11.Li-Jian Chen,Nan Wang,Xin-Dong Wang,Shi-Yun Ai*. Protein-Directed in Situ Synthesis of Platinum Nanoparticles with Superior Peroxidase-Like Activity, and Their Use for Photometric Determination of Hydrogen Peroxide.Microchimica Acta, 2013, 180: 1517-1522.
1. 2020年度中国博士后创新人才支持计划优秀创新成果;
2. 2019年度中国分析测试协会科学技术奖-CAIA特等奖(排名第5)。
1.陈丽建,严秀平.一种可近红外光余辉成像示踪的纳米药物载体及其制备,ZL201911171581.4;
2.陈丽建,严秀平,龚嘉华,王江悦,刘瑶瑶.一种可余辉光监测缓释抗菌的锗酸锌基质纳米材料及其制备方法,ZL202110633407.8。